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The Science Behind Longevity Supplements for Dogs...

By Ashley Decker, Chief Scientist, Plentum |October 21, 2025

Wellness

The purpose of longevity support in dogs is to enhance their health span through cellular aging prevention rather than extending their lifespan.
The main factors that lead to aging in dogs consist of oxidative stress and chronic inflammation known as "inflammaging" and declining mitochondrial energy production.
Scientifically-backed ingredients such as antioxidants and Omega-3s and NAD+ precursors directly benefit cellular pathways which leads to better aging outcomes from the inside out.

A dignified grey-muzzled senior Labrador resting serenely in warm window light, illustrating the science behind longevity supplements for dogs

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Clinical Evidence

Publication	Year	n-size	Primary Endpoint	Result	Source
Stübing et al., Vet Sci	2024	27 dogs	Clinical course in acute diarrhea + core microbiota	Comparable resolution to metronidazole; better preservation of beneficial gut microbiota	PMID 38787169

Regulatory Notice These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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