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Compare formulas
Five formulas, each focused on one area
Microbiome Care is the daily foundation. Gut Restore, Calming Care, Itch & Immune Care and Metabolic Care each focus on one area of wellbeing. Every one is a powder with no chew binders and no artificial flavors or colors. The only other addition is a trace of what keeps the powder free-flowing.
- 5formulas
- 2 gevery sachet
- 30sachets per box
Why a powder
More of every gram is active
A powder needs no chew binders or artificial flavors or colors. The only addition is a trace of what keeps it free-flowing.
| Plentum powder sachet | A typical chew | |
|---|---|---|
| Binders and fillers | None. A powder does not need them to hold a shape. | Usually needed to hold the shape and bulk of the chew. |
| Flavors, colors, flow | No artificial flavors or colors. Only a trace of what keeps the powder free-flowing. | Varies by brand. Check the other-ingredients list. |
| Actives per serving | More of each gram is active: up to 977 mg of actives in one 2 g sachet. | Actives share the serving with the chew matrix and flavor base. |
| Doses | Every dose in mg on the label, ingredient by ingredient. | Some labels list a blend total only. |
| Dosing by weight | One pre-measured 2 g sachet, 1 to 4 a day by weight. | Fixed piece sizes and counts. |
| How it is given | Mix into any food: dry, wet or a warm-water gravy. | Offered as a treat, or hidden in food. |
This is a fair comparison with typical chews in general, not with any brand. A chew can be a good choice. Compare the label.
The five formulas
Side by side
Microbiome Care is the foundation. The other four each focus on one area of wellbeing.
| Per 2 g sachet | |||||
|---|---|---|---|---|---|
| In every sachet | One pre-measured 2 g sachet with no chew binders and no artificial flavors or colors. The only addition is a trace of what keeps the powder free-flowing, and it mixes into any food. | One pre-measured 2 g sachet with no chew binders and no artificial flavors or colors. The only addition is a trace of what keeps the powder free-flowing, and it mixes into any food. | One pre-measured 2 g sachet with no chew binders and no artificial flavors or colors. The only addition is a trace of what keeps the powder free-flowing, and it mixes into any food. | One pre-measured 2 g sachet with no chew binders and no artificial flavors or colors. The only addition is a trace of what keeps the powder free-flowing, and it mixes into any food. | One pre-measured 2 g sachet with no chew binders and no artificial flavors or colors. The only addition is a trace of what keeps the powder free-flowing, and it mixes into any food. |
| What it is for | Daily gut and oral-health support in one sachet, plus skin and coat nutrients. | Supports normal bowel function and healthy stool consistency, and helps maintain proper gut flora during dietary change or stress. | Supports a calm and relaxed demeanor during situational stress, such as thunderstorms and travel, and promotes a healthy gut-brain axis. | Supports a normal immune system response to environmental and seasonal triggers, a healthy coat, and the gut-skin axis. | Supports proper weight management, alongside portion control and exercise. |
| Main actives (per sachet) |
Also licorice root 50 mg, zinc methionine 5 mg, selenomethionine 20 mcg, vitamin E 25 IU. |
Also Jerusalem artichoke inulin 50 mg. |
Also probiotic blend 75 mg, chamomile 75 mg, passionflower 75 mg, valerian root 50 mg, ashwagandha (KSM-66) 50 mg, vitamin B6 2 mg. |
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Also chia seed 50 mg and chitosan 50 mg. |
| Live probiotic | None. A postbiotic and prebiotic formula with no live cultures. | Yes. Five strains (L. casei K9-1, L. fermentum K9-2, L. brevis WF-1B, L. reuteri WF-1, S. boulardii), 10 billion CFU per label. | Yes. Five strains (L. casei K9-1, L. fermentum K9-2, L. brevis WF-1B, L. reuteri WF-1, S. boulardii), 10 billion CFU per label. | Yes. Four strains (L. casei K9-1, L. fermentum K9-2, L. brevis WF-1B, L. reuteri WF-1), 2 billion CFU per label. | Yes. B. animalis lactis and L. gasseri, 2 billion CFU per label. |
| Postbiotic | Oral-health postbiotic | Yeast cell wall postbiotic | A postbiotic | Canine immune-health postbiotic | Pediococcus acidilactici postbiotic blend |
| Who it is for | Dogs of different sizes and life stages, as the everyday base. | Dogs facing a food change, boarding, travel or a stressful week. | Dogs who get worked up by storms, fireworks, car rides, vet visits or grooming. | Dogs whose coat and skin need extra support, including through seasonal changes. | Adult dogs on a portion-control and exercise plan. It works alongside diet, not instead of it. |
| Price a day, by dog size |
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| Often used with | The base layer. Often given under a targeted formula. | Some dog parents use it for a set period, then carry on with Microbiome Care. Both contain inulin, so fiber overlaps. | A seasonal add-on to Microbiome Care. | Often paired with Microbiome Care. They share colostrum and omega-3, so the doses add up. | Often used alongside Microbiome Care, with portion control and exercise. |
| Also in the formula | Contains fish oil and bovine colostrum. | Contains brewer's yeast and a probiotic yeast (S. boulardii). | Contains brewer's yeast and a probiotic yeast (S. boulardii). | Contains bovine colostrum and brewer's yeast. The DHA is algal, so it is fish-free. | Contains brewer's yeast and chitosan, a fiber. Mix with water or wet food. |

Microbiome Care
The daily foundation- In every sachet
- One pre-measured 2 g sachet with no chew binders and no artificial flavors or colors. The only addition is a trace of what keeps the powder free-flowing, and it mixes into any food.
- What it is for
- Daily gut and oral-health support in one sachet, plus skin and coat nutrients.
- Main actives (per sachet)
- Oral-health postbiotic 125 mg
- Fish oil 150 mg
- Colostrum 100 mg
- Inulin 100 mg
- L-glutamine 100 mg
Also licorice root 50 mg, zinc methionine 5 mg, selenomethionine 20 mcg, vitamin E 25 IU.
- Live probiotic
- None. A postbiotic and prebiotic formula with no live cultures.
- Postbiotic
- Oral-health postbiotic
- Who it is for
- Dogs of different sizes and life stages, as the everyday base.
- Price a day, by dog size
- Up to 20 lb$1.17 a day
- 20–50 lb$2.22 a day
- Over 50 lb$3.25 a day
- Often used with
- The base layer. Often given under a targeted formula.
- Also in the formula
- Contains fish oil and bovine colostrum.

Gut Restore
Gut support- In every sachet
- One pre-measured 2 g sachet with no chew binders and no artificial flavors or colors. The only addition is a trace of what keeps the powder free-flowing, and it mixes into any food.
- What it is for
- Supports normal bowel function and healthy stool consistency, and helps maintain proper gut flora during dietary change or stress.
- Main actives (per sachet)
- Proprietary probiotic blend 300 mg (10 billion CFU)
- Psyllium husk 200 mg
- Slippery elm bark 150 mg
- Organic pumpkin 150 mg
- Yeast cell wall postbiotic 75 mg
Also Jerusalem artichoke inulin 50 mg.
- Live probiotic
- Yes. Five strains (L. casei K9-1, L. fermentum K9-2, L. brevis WF-1B, L. reuteri WF-1, S. boulardii), 10 billion CFU per label.
- Postbiotic
- Yeast cell wall postbiotic
- Who it is for
- Dogs facing a food change, boarding, travel or a stressful week.
- Price a day, by dog size
- Under 25 lb$1.50 a day
- 26–50 lb$2.87 a day
- 51–75 lb$4.00 a day
- Over 75 lb$5.00 a day
- Often used with
- Some dog parents use it for a set period, then carry on with Microbiome Care. Both contain inulin, so fiber overlaps.
- Also in the formula
- Contains brewer's yeast and a probiotic yeast (S. boulardii).

Calming Care
Calming support- In every sachet
- One pre-measured 2 g sachet with no chew binders and no artificial flavors or colors. The only addition is a trace of what keeps the powder free-flowing, and it mixes into any food.
- What it is for
- Supports a calm and relaxed demeanor during situational stress, such as thunderstorms and travel, and promotes a healthy gut-brain axis.
- Main actives (per sachet)
- L-theanine (Suntheanine) 200 mg
- GABA 150 mg
- Magnesium 100 mg
- L-tryptophan 100 mg
- Postbiotic 100 mg
Also probiotic blend 75 mg, chamomile 75 mg, passionflower 75 mg, valerian root 50 mg, ashwagandha (KSM-66) 50 mg, vitamin B6 2 mg.
- Live probiotic
- Yes. Five strains (L. casei K9-1, L. fermentum K9-2, L. brevis WF-1B, L. reuteri WF-1, S. boulardii), 10 billion CFU per label.
- Postbiotic
- A postbiotic
- Who it is for
- Dogs who get worked up by storms, fireworks, car rides, vet visits or grooming.
- Price a day, by dog size
- Under 25 lb$1.50 a day
- 26–50 lb$2.87 a day
- 51–75 lb$4.00 a day
- Over 75 lb$5.00 a day
- Often used with
- A seasonal add-on to Microbiome Care.
- Also in the formula
- Contains brewer's yeast and a probiotic yeast (S. boulardii).

Itch & Immune Care
The gut-skin axis- In every sachet
- One pre-measured 2 g sachet with no chew binders and no artificial flavors or colors. The only addition is a trace of what keeps the powder free-flowing, and it mixes into any food.
- What it is for
- Supports a normal immune system response to environmental and seasonal triggers, a healthy coat, and the gut-skin axis.
- Main actives (per sachet)
- Canine immune-health postbiotic 250 mg
- Algal DHA 250 mg
- Colostrum (30% IgG, bovine) 150 mg
- Proprietary probiotic blend 150 mg (2 billion CFU)
- Quercetin 100 mg
- Spirulina 75 mg
- Live probiotic
- Yes. Four strains (L. casei K9-1, L. fermentum K9-2, L. brevis WF-1B, L. reuteri WF-1), 2 billion CFU per label.
- Postbiotic
- Canine immune-health postbiotic
- Who it is for
- Dogs whose coat and skin need extra support, including through seasonal changes.
- Price a day, by dog size
- Under 25 lb$1.50 a day
- 26–50 lb$2.87 a day
- 51–75 lb$4.00 a day
- Over 75 lb$5.00 a day
- Often used with
- Often paired with Microbiome Care. They share colostrum and omega-3, so the doses add up.
- Also in the formula
- Contains bovine colostrum and brewer's yeast. The DHA is algal, so it is fish-free.

Metabolic Care
Healthy weight- In every sachet
- One pre-measured 2 g sachet with no chew binders and no artificial flavors or colors. The only addition is a trace of what keeps the powder free-flowing, and it mixes into any food.
- What it is for
- Supports proper weight management, alongside portion control and exercise.
- Main actives (per sachet)
- Pediococcus acidilactici postbiotic blend 200 mg
- Acacia fiber 175 mg
- Probiotic blend 100 mg (2 billion CFU)
- L-carnitine 75 mg
- White kidney bean extract 50 mg
Also chia seed 50 mg and chitosan 50 mg.
- Live probiotic
- Yes. B. animalis lactis and L. gasseri, 2 billion CFU per label.
- Postbiotic
- Pediococcus acidilactici postbiotic blend
- Who it is for
- Adult dogs on a portion-control and exercise plan. It works alongside diet, not instead of it.
- Price a day, by dog size
- Under 25 lb$1.50 a day
- 26–50 lb$2.87 a day
- 51–75 lb$4.00 a day
- Over 75 lb$5.00 a day
- Often used with
- Often used alongside Microbiome Care, with portion control and exercise.
- Also in the formula
- Contains brewer's yeast and chitosan, a fiber. Mix with water or wet food.
Doses are per 2 g sachet. Dogs take 1 to 4 sachets a day by weight. Price a day is the one-time box price divided by 30 days at that size.
Which one?
Start with what matters most
Pick the closest match to see the formula that fits, described in the label's words.
Microbiome Care
Start here. Gut, mouth, skin and coat nutrients in one daily sachet. It has no live cultures.
Gut Restore
Supports normal bowel function and healthy stool consistency, and helps maintain gut flora during dietary change or stress.
Calming Care
Supports a calm and relaxed demeanor during situational stress.
Itch & Immune Care
Supports a normal immune response to environmental and seasonal triggers, and a healthy coat.
Metabolic Care
Supports proper weight management. It works alongside portion control and exercise, not instead of them.
A starting point for choosing a formula.
Stacking
Using more than one
Many dogs take Microbiome Care with a targeted formula. Here are the rules, and a check for repeated actives.
- Start with one.Begin with the formula that matches your dog's main need. You can add a second later, once the first is part of the routine.
- Count every sachet.Each formula is dosed by weight on its own, 1 to 4 sachets a day. Two formulas means two doses.
- Check what repeats.A few actives appear in more than one formula, so doses add up. The check below shows which, and by how much.
- No added-effect claims.Each formula stands on its own. We do not claim that using two together does more than the sum of what is on each label.
Stack check
Pick the formulas you are considering.
Dog weight in lb
Before you start
Before you add a supplement
Talk to your veterinarian before adding a supplement, especially if your dog takes medication, is pregnant or nursing, has a diagnosed condition, or has reacted to new foods.
If something doesn't match
We check these pages against each formula. If a page and your box ever differ, go by the box and tell us through the contact page.